Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
Primary microcephaly is a clinical feature of several human telomere disorder syndromes. Here the authors reveal a role of Microcephalin 1 in promoting telomere replication and repair.
Bibliographic Details
| Main Authors: |
Alessandro Cicconi,
Rekha Rai,
Xuexue Xiong,
Cayla Broton,
Amer Al-Hiyasat,
Chunyi Hu,
Siying Dong,
Wenqi Sun,
Jennifer Garbarino,
Ranjit S. Bindra,
Carl Schildkraut,
Yong Chen,
Sandy Chang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-19674-0
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