The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure

The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure

The mechanisms for the establishment and the persistence of the latent HIV-1 reservoir remain to be completely defined. HIV-1 infection is characterised by the integration of the reverse transcribed proviral DNA into the host's genome. This integrated proviral DNA can remain replication silent,...

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Bibliographic Details
Main Authors: Maja Kiselinova, Ward De Spiegelaere, Linos Vandekerckhove
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Journal of Virus Eradication
Subjects:
integration site
HIV-1
HIV-1 persistence
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020304611

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