Vas deferens infiltration by prostate cancer on prostate-specific membrane antigen-targeted18F-DCFPyL positron emission tomography/computed tomography: A unique visual pattern

• Main Authors: Yafu Yin, Channing J Paller, Martin G Pomper, Kenneth J Pienta, Michael A Gorin, Steven P Rowe
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2019-01-01
• Series: World Journal of Nuclear Medicine
• Subjects: 18f-dcfpyl; positron emission tomography/computed tomography; prostate cancer; prostate-specific membrane; vas deferens
• Online Access: http://www.wjnm.org/article.asp?issn=1450-1147;year=2019;volume=18;issue=4;spage=424;epage=427;aulast=Yin
• ISSN: 1450-1147; 1607-3312

New radiotracers for positron emission tomography imaging that target prostate-specific membrane antigen (PSMA) have emerged as important clinical tools for imaging prostate cancer (PCa). PSMA-targeted radiotracers have demonstrated high sensitivity and high specificity for detecting sites of PCa and are demonstrably superior to conventional imaging modalities such as computed tomography and bone scan. Vas deferens invasion is a rarely encountered poor prognostic feature of PCa. In this case report, we describe a novel pattern of radiotracer uptake in a patient with PCa imaged with PSMA-targeted18F-DCFPyL positron emission tomography/computed tomography that is consistent with diffuse vas deferens involvement.