Genetic engineering of mesenchymal stromal cells for cancer therapy: turning partners in crime into Trojan horses

Genetic engineering of mesenchymal stromal cells for cancer therapy: turning partners in crime into Trojan horses

Mesenchymal stromal cells (MSCs) are adult progenitor cells with a high migratory and differentiation potential, which influence a broad range of biological functions in almost every tissue of the body. Among other mechanisms, MSCs do so by the secretion of molecular cues, differentiation toward mor...

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Bibliographic Details
Main Authors: Niess Hanno, Thomas Michael N., Schiergens Tobias S., Kleespies Axel, Jauch Karl-Walter, Bruns Christiane, Werner Jens, Nelson Peter J., Angele Martin K.
Format: Article
Language:English
Published: De Gruyter 2016-09-01
Series:Innovative Surgical Science
Subjects:
hsv-tk
mesenchymal stromal cells
msc
suicide gene therapy
tumor stroma
Online Access:https://doi.org/10.1515/iss-2016-0005

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