Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations.
Over evolutionary time, members of a superfamily of homologous proteins sharing a common structural core diverge into subgroups filling various functional niches. At the sequence level, such divergence appears as correlations that arise from residue patterns distinct to each subgroup. Such a superfa...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5225019?pdf=render |