Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae.

Meiotic chromosomes assemble characteristic "axial element" structures that are essential for fertility and provide the chromosomal context for meiotic recombination, synapsis and checkpoint signaling. Whether these meiotic processes are equally dependent on axial element integrity has rem...

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Bibliographic Details
Main Authors: Tovah E Markowitz, Daniel Suarez, Hannah G Blitzblau, Neem J Patel, Andrew L Markhard, Amy J MacQueen, Andreas Hochwagen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1006928