The neuroprotective effect of miRNA-132 against amyloid β-protein-induced neuronal damage via upregulation of brain-derived neurotrophic factor

The neuroprotective effect of miRNA-132 against amyloid β-protein-induced neuronal damage via upregulation of brain-derived neurotrophic factor

<p><strong>Background</strong> Brain-derived neurotrophic factor (BDNF) plays a crucial role in the pathogenesis of Alzheimer's disease (AD). MicroRNA (miRNA)-132, which is widely expressed in neurons, is involved in BDNF-mediated neural development by regulating the expres...

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Bibliographic Details
Main Authors: Lei XIANG, Yan-ping REN, Yi-jun SONG
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2016-07-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
MicroRNAs
Brain-derived neurotrophic factor
Amyloid beta-protein
Neurons
Polymerase chain reaction
Cells, cultured
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/1428

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