Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer

<p>Abstract</p> <p>Background</p> <p>We previously reported that survivin-2B, a splicing variant of survivin, was expressed in various types of tumors and that survivin-2B peptide might serve as a potent immunogenic cancer vaccine. The objective of this study was to exa...

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Main Authors: Asanuma Hiroko, Hirohashi Yoshihiko, Yagihashi Atsuhito, Toyota Nobuhiko, Torigoe Toshihiko, Kimura Yasutoshi, Yamaguchi Koji, Furuhata Tomohisa, Hata Fumitake, Katsuramaki Tadashi, Ohmura Tosei, Iwayama Yuji, Tsuruma Tetsuhiro, Shimozawa Kumiko, Okazaki Minoru, Mizushima Yasuhiro, Nomura Naohiro, Sato Noriyuki, Hirata Koichi
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/24