Individual Impact of Distinct Polysialic Acid Chain Lengths on the Cytotoxicity of Histone H1, H2A, H2B, H3 and H4

Individual Impact of Distinct Polysialic Acid Chain Lengths on the Cytotoxicity of Histone H1, H2A, H2B, H3 and H4

Neutrophils are able to neutralize pathogens by phagocytosis, by the release of antimicrobial components, as well as by the formation of neutrophil extracellular traps (NETs). The latter possibility is a DNA-meshwork mainly consisting of highly concentrated extracellular histones, which are not only...

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Bibliographic Details
Main Authors: Kristina Zlatina, Thomas Lütteke, Sebastian P. Galuska
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Polymers
Subjects:
polysialic acid
histones
neutrophil extracellular traps
Online Access:https://www.mdpi.com/2073-4360/9/12/720

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