Si-Miao-Yong-An Decoction Protects Against Cardiac Hypertrophy and Dysfunction by Inhibiting Platelet Aggregation and Activation

Si-Miao-Yong-An Decoction Protects Against Cardiac Hypertrophy and Dysfunction by Inhibiting Platelet Aggregation and Activation

Objective: The aim of this study was to determine whether Si-Miao-Yong-An decoction (SMYAD) could ameliorate pressure overload-induced heart hypertrophy and its mechanisms.Methods: C57BL/6 mice were subjected to either sham or transverse aortic constriction (TAC) surgery to induce heart hypertrophy....

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Bibliographic Details
Main Authors: Congping Su, Qing Wang, Huimin Zhang, Wenchao Jiao, Hui Luo, Lin Li, Xiangyang Chen, Bin Liu, Xue Yu, Sen Li, Wei Wang, Shuzhen Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
Si-Miao-Yong-An decoction
cardiac hypertrophy
heart failure
platelet activation
transverse aortic constriction
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00990/full

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