Accuracy of spiked cell counting methods for designing a pre-clinical tumorigenicity study model

Background: Evaluations for the tumorigenicity of transplantation of stem cell products is mandatory for clinical application. It is of importance to establish a system to accurately quantify contaminated tumorigenic cells regardless of the format of stem cell product. In the present report, we aime...

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Bibliographic Details
Main Authors: Hiroaki Osada, Masahide Kawatou, Masafumi Takeda, Jun-ichiro Jo, Takashi Murakami, Yasuhiko Tabata, Kenji Minatoya, Jun K. Yamashita, Hidetoshi Masumoto
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020312676