Effectors Targeting the Unfolded Protein Response during Intracellular Bacterial Infection

Effectors Targeting the Unfolded Protein Response during Intracellular Bacterial Infection

The unfolded protein response (UPR) is a homeostatic response to endoplasmic reticulum (ER) stress within eukaryotic cells. The UPR initiates transcriptional and post-transcriptional programs to resolve ER stress; or, if ER stress is severe or prolonged, initiates apoptosis. ER stress is a common fe...

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Bibliographic Details
Main Authors: Manal H. Alshareef, Elizabeth L. Hartland, Kathleen McCaffrey
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Microorganisms
Subjects:
ER stress
UPR
bacteria
infection
secretion systems
effector proteins
Online Access:https://www.mdpi.com/2076-2607/9/4/705

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