Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations

Over the last decade, new therapeutics in the form of anti-angiogenic treatment, synthetic lethality, and checkpoint inhibition have offered new options for the treatment of ovarian cancer. This review summarizes studies related to these treatment modalities and additionally novel combinations that...

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Main Authors: Marisa C Liu, Krishnansu S Tewari
Format: Article
Language:English
Published: BioExcel Publishing Ltd 2018-12-01
Series:Drugs in Context
Subjects:
Online Access:https://www.drugsincontext.com/antiangiogenesis-therapy-synthetic-lethality-and-checkpoint-inhibition-in-ovarian-cancer
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spelling doaj-1fc5bdf633104df1a16c915a36c7ca422020-11-24T21:33:17ZengBioExcel Publishing LtdDrugs in Context1740-43981740-43982018-12-0171910.7573/dic.212558Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinationsMarisa C LiuKrishnansu S TewariOver the last decade, new therapeutics in the form of anti-angiogenic treatment, synthetic lethality, and checkpoint inhibition have offered new options for the treatment of ovarian cancer. This review summarizes studies related to these treatment modalities and additionally novel combinations that offer a veritable therapeutic matrix for clinicians to choose from.https://www.drugsincontext.com/antiangiogenesis-therapy-synthetic-lethality-and-checkpoint-inhibition-in-ovarian-cancerbevacizumabcheckpoint inhibitorchemotherapyovarian cancerPARP inhibitor
collection DOAJ
language English
format Article
sources DOAJ
author Marisa C Liu
Krishnansu S Tewari
spellingShingle Marisa C Liu
Krishnansu S Tewari
Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
Drugs in Context
bevacizumab
checkpoint inhibitor
chemotherapy
ovarian cancer
PARP inhibitor
author_facet Marisa C Liu
Krishnansu S Tewari
author_sort Marisa C Liu
title Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
title_short Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
title_full Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
title_fullStr Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
title_full_unstemmed Anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
title_sort anti-angiogenesis therapy, synthetic lethality, and checkpoint inhibition in ovarian cancer: state of the science and novel combinations
publisher BioExcel Publishing Ltd
series Drugs in Context
issn 1740-4398
1740-4398
publishDate 2018-12-01
description Over the last decade, new therapeutics in the form of anti-angiogenic treatment, synthetic lethality, and checkpoint inhibition have offered new options for the treatment of ovarian cancer. This review summarizes studies related to these treatment modalities and additionally novel combinations that offer a veritable therapeutic matrix for clinicians to choose from.
topic bevacizumab
checkpoint inhibitor
chemotherapy
ovarian cancer
PARP inhibitor
url https://www.drugsincontext.com/antiangiogenesis-therapy-synthetic-lethality-and-checkpoint-inhibition-in-ovarian-cancer
work_keys_str_mv AT marisacliu antiangiogenesistherapysyntheticlethalityandcheckpointinhibitioninovariancancerstateofthescienceandnovelcombinations
AT krishnansustewari antiangiogenesistherapysyntheticlethalityandcheckpointinhibitioninovariancancerstateofthescienceandnovelcombinations
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