Master protocol trials in oncology: Review and new trial designs

In oncology, next generation sequencing and comprehensive genomic profiling have enabled the detailed classification of tumors using molecular biology. However, it is unrealistic to conduct phase I–III trials according to each sub-population based on patient molecular subtypes. Common protocols that...

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Bibliographic Details
Main Authors: Akihiro Hirakawa, Junichi Asano, Hiroyuki Sato, Satoshi Teramukai
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865418300565