ß-Hydroxybutyrate Activates the NF-κB Signaling Pathway to Promote the Expression of Pro-Inflammatory Factors in Calf Hepatocytes

ß-Hydroxybutyrate Activates the NF-κB Signaling Pathway to Promote the Expression of Pro-Inflammatory Factors in Calf Hepatocytes

Background/Aims: ß-hydroxybutyrate (BHBA) is the major component of ketone bodies in ketosis. Dairy cows with ketosis often undergo oxidative stress. BHBA is related to the inflammation involved in other diseases of dairy cattle. However, whether BHBA can induce inflammatory injury in dairy cow hepa...

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Bibliographic Details
Main Authors: Xiaoxia Shi, Xinwei Li, Dangdang Li, Yu Li, Yuxiang Song, Qinghua Deng, Jianguo Wang, Yuhang Zhang, Hongyan Ding, Liheng Yin, Yuming Zhang, Zhe Wang, Xiaobing Li, Guowen Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oxidative stress
NF-κB pathway
Inflammatory injury
Bovine hepatocytes
Online Access:http://www.karger.com/Article/FullText/358664

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