Identification of Spt5 target genes in zebrafish development reveals its dual activity in vivo.

Spt5 is a conserved essential protein that represses or stimulates transcription elongation in vitro. Immunolocalization studies on Drosophila polytene chromosomes suggest that Spt5 is associated with many loci throughout the genome. However, little is known about the prevalence and identity of Spt5...

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Bibliographic Details
Main Authors: Keerthi Krishnan, Nathan Salomonis, Su Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2575381?pdf=render