Engineering induction of singular neural rosette emergence within hPSC-derived tissues

Engineering induction of singular neural rosette emergence within hPSC-derived tissues

Human pluripotent stem cell (hPSC)-derived neural organoids display unprecedented emergent properties. Yet in contrast to the singular neuroepithelial tube from which the entire central nervous system (CNS) develops in vivo, current organoid protocols yield tissues with multiple neuroepithelial unit...

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Bibliographic Details
Main Authors:	Gavin T Knight, Brady F Lundin, Nisha Iyer, Lydia MT Ashton, William A Sethares, Rebecca M Willett, Randolph Scott Ashton
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2018-10-01
Series:	eLife
Subjects:	human pluripotent stem cells neural stem cells organoid morphogenesis neural rosette stem cell bioengineering advanced biomanufacturing
Online Access:	https://elifesciences.org/articles/37549

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