Serial swept source optical coherence tomography of a cotton wool spot following SARS CoV2 infection

• Main Authors: Mauli Shah, Jyotirmay Biswas
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: ace2 receptor; cd147; cotton wool spot; sars-cov2
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=10;spage=2867;epage=2868;aulast=Shah

A 33-year-old male presented with history of blurring of vision in the left eye for two months. He was seen by the local ophthalmologist and diagnosed as nongranulomatous anterior uveitis in the left eye with normal fundus. He had history of fever 20 days back and was diagnosed positive for COVID-19 by RT-PCR. He presented with acute anterior uveitis in the left eye. Fundus examination revealed a cotton wool spot close to the fovea, which was confirmed by swept-source optical coherence tomography (SS-OCT) of the macula. The patient after two months' follow-up showed resolution of the cotton wool spot, which was confirmed by SS-OCT. Our case indicates that cotton wool spot can be an ocular manifestation of COVID-19 infection, and swept-source optical coherence tomography can precisely document the resolution of the lesion.