Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria

Background: There is controversy about the global distribution of intracranial tumors (ICTs). The previous reports from Africa suggested low frequency and different pattern of distribution of brain tumors from what obtains in other continents. The limitations at that time, including paucity of diagn...

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Main Authors: Chika Anele Ndubuisi, Samuel C. Ohaegbulam, Linda U. Iroegbu, Mike Ezeali Ekuma, Wilfred C. Mezue, Uwadiegwu Alphonsus Erechukwu
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2017-10-01
Series:Journal of Neurosciences in Rural Practice
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/jnrp.jnrp_155_17
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spelling doaj-1f98e1cef4e643a69773cb1bd783b2d32021-04-02T11:47:20ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552017-10-01080458559010.4103/jnrp.jnrp_155_17Histologically Confirmed Intracranial Tumors Managed at Enugu, NigeriaChika Anele Ndubuisi0Samuel C. Ohaegbulam1Linda U. Iroegbu2Mike Ezeali Ekuma3Wilfred C. Mezue4Uwadiegwu Alphonsus Erechukwu5Department of Neurosurgery, Memfys Hospital for Neurosurgery, Enugu, NigeriaDepartment of Neurosurgery, Memfys Hospital for Neurosurgery, Enugu, NigeriaDepartment of Neurosurgery, Memfys Hospital for Neurosurgery, Enugu, NigeriaDepartment of Neurosurgery, Memfys Hospital for Neurosurgery, Enugu, NigeriaDepartment of Neurosurgery, Memfys Hospital for Neurosurgery, Enugu, NigeriaDepartment of Neurosurgery, Memfys Hospital for Neurosurgery, Enugu, NigeriaBackground: There is controversy about the global distribution of intracranial tumors (ICTs). The previous reports from Africa suggested low frequency and different pattern of distribution of brain tumors from what obtains in other continents. The limitations at that time, including paucity of diagnostic facilities and personnel, have improved. Objective: The objective of this study is to analyze the current trend and distribution of histology confirmed brain tumors managed in Enugu, in a decade. Methods: A retrospective analysis of ICTs managed between 2006 and 2015 at Memfys Hospital, Enugu. Only cases with conclusive histology report were analyzed. The World Health Organization ICT classification was used. Results: This study reviewed 252 patients out of 612 neuroimaging diagnosed brain tumors. Mean age was 42.8 years and male-to-female ratio was 1.2:1.0. Annual frequency increased from 11 in 2006 to 55 in 2015. Metastatic brain tumors accounted for 5.6%, and infratentorial tumors represented 16.3%. Frequency of the common primary tumors were meningioma (32.9%), glioma (23.8%), pituitary adenomas (13.5%), and craniopharyngioma (7.5%) (P =0.001). Vestibular schwannoma accounted for 1.2%. Meningioma did not have gender difference (P =0.714). Medulloblastoma, glioma, and craniopharyngioma were the most common pediatric tumors. About 8.7% presented unconscious (P < 0.001). There was no significant difference between radiology and histology diagnosis (P =0.932). Conclusion: Meningioma is the most frequent tumor with increasing male incidence, but the frequency of glioma is increasing. Metastasis, acoustic schwannoma, lymphoma, and germ cell tumors seem to be uncommon. Late presentation is the rule.http://www.thieme-connect.de/DOI/DOI?10.4103/jnrp.jnrp_155_17 epidemiology geographical-neurosurgery intracranial-tumors
collection DOAJ
language English
format Article
sources DOAJ
author Chika Anele Ndubuisi
Samuel C. Ohaegbulam
Linda U. Iroegbu
Mike Ezeali Ekuma
Wilfred C. Mezue
Uwadiegwu Alphonsus Erechukwu
spellingShingle Chika Anele Ndubuisi
Samuel C. Ohaegbulam
Linda U. Iroegbu
Mike Ezeali Ekuma
Wilfred C. Mezue
Uwadiegwu Alphonsus Erechukwu
Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria
Journal of Neurosciences in Rural Practice
epidemiology
geographical-neurosurgery
intracranial-tumors
author_facet Chika Anele Ndubuisi
Samuel C. Ohaegbulam
Linda U. Iroegbu
Mike Ezeali Ekuma
Wilfred C. Mezue
Uwadiegwu Alphonsus Erechukwu
author_sort Chika Anele Ndubuisi
title Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria
title_short Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria
title_full Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria
title_fullStr Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria
title_full_unstemmed Histologically Confirmed Intracranial Tumors Managed at Enugu, Nigeria
title_sort histologically confirmed intracranial tumors managed at enugu, nigeria
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
series Journal of Neurosciences in Rural Practice
issn 0976-3147
0976-3155
publishDate 2017-10-01
description Background: There is controversy about the global distribution of intracranial tumors (ICTs). The previous reports from Africa suggested low frequency and different pattern of distribution of brain tumors from what obtains in other continents. The limitations at that time, including paucity of diagnostic facilities and personnel, have improved. Objective: The objective of this study is to analyze the current trend and distribution of histology confirmed brain tumors managed in Enugu, in a decade. Methods: A retrospective analysis of ICTs managed between 2006 and 2015 at Memfys Hospital, Enugu. Only cases with conclusive histology report were analyzed. The World Health Organization ICT classification was used. Results: This study reviewed 252 patients out of 612 neuroimaging diagnosed brain tumors. Mean age was 42.8 years and male-to-female ratio was 1.2:1.0. Annual frequency increased from 11 in 2006 to 55 in 2015. Metastatic brain tumors accounted for 5.6%, and infratentorial tumors represented 16.3%. Frequency of the common primary tumors were meningioma (32.9%), glioma (23.8%), pituitary adenomas (13.5%), and craniopharyngioma (7.5%) (P =0.001). Vestibular schwannoma accounted for 1.2%. Meningioma did not have gender difference (P =0.714). Medulloblastoma, glioma, and craniopharyngioma were the most common pediatric tumors. About 8.7% presented unconscious (P < 0.001). There was no significant difference between radiology and histology diagnosis (P =0.932). Conclusion: Meningioma is the most frequent tumor with increasing male incidence, but the frequency of glioma is increasing. Metastasis, acoustic schwannoma, lymphoma, and germ cell tumors seem to be uncommon. Late presentation is the rule.
topic epidemiology
geographical-neurosurgery
intracranial-tumors
url http://www.thieme-connect.de/DOI/DOI?10.4103/jnrp.jnrp_155_17
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AT lindauiroegbu histologicallyconfirmedintracranialtumorsmanagedatenugunigeria
AT mikeezealiekuma histologicallyconfirmedintracranialtumorsmanagedatenugunigeria
AT wilfredcmezue histologicallyconfirmedintracranialtumorsmanagedatenugunigeria
AT uwadiegwualphonsuserechukwu histologicallyconfirmedintracranialtumorsmanagedatenugunigeria
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