Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Endothelin-1 (ET-1) and its two receptors, endothelin receptor A (ETAR) and endothelin receptor B (ETBR) exhibit deregulated overexprerssion in pancreatic ductal adenocarcinoma (PDAC) and pancreatitis. We examined the expression pattern of endothelin (ET) axis components in the murine models of chro...

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Bibliographic Details
Main Authors: Suprit Gupta, Avi Prajapati, Mansi Gulati, Shailendra K. Gautam, Sushil Kumar, Vipin Dalal, Geoffrey A. Talmon, Satyanarayana Rachagani, Maneesh Jain
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619302544

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