Stepping toward a Macaque Model of HIV-1 Induced AIDS

HIV-1 exhibits a narrow host range, hindering the development of a robust animal model of pathogenesis. Past studies have demonstrated that the restricted host range of HIV-1 may be largely due to the inability of the virus to antagonize and evade effector molecules of the interferon response in oth...

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Bibliographic Details
Main Author: Jason T. Kimata
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/6/9/3643