The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study

Abstract Background The need for early antibiotics in the intensive care unit (ICU) is often balanced against the goal of antibiotic stewardship. Long-course antibiotics increase the burden of antimicrobial resistance within colonizing gut bacteria, but the dynamics of this process are not fully und...

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Main Authors: Christian Munck, Ravi U. Sheth, Edward Cuaresma, Jessica Weidler, Stephania L. Stump, Philip Zachariah, David H. Chong, Anne-Catrin Uhlemann, Julian A. Abrams, Harris H. Wang, Daniel E. Freedberg
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-020-03061-8