Current research status of precancerous dysplastic nodules in hepatocellular carcinoma

• Main Authors: JIAO Junzhe, LI Jingtao, YAN Shuguang
• Format: Article
• Language: zho
• Published: Editorial Department of Journal of Clinical Hepatology 2017-05-01
• Series: Linchuang Gandanbing Zazhi
• Online Access: http://www.lcgdbzz.org/qk_content.asp?id=8213

Dysplastic nodule (DN) is an important stage for precancerous hepatocellular carcinoma (HCC) lesions progressing to HCC and has a very high risk of canceration. According to the difference in atypia, DN is classified into low-grade DN (LGDN) and high-grade DN (HGDN). This article summarizes the pathological features, radiological features, and biomarkers of LGDN and HGDN, briefly describes the risk of the canceration of DN into HCC, and points out that it is necessary to enhance the knowledge of DN, the precancerous HCC lesions, in clinical physicians. DN screening to identify nodules with a high risk of canceration and related intervention help to prevent the development of HCC.