COMPARISON OF COLORIMETRIC AND CHEMILUMINESCENT ELISA TESTS FOR DETECTION OF IgG ANTIBODIES TO HUMAN EPO IN THE SERA OF EXPERIMENTAL ANIMALS
Production of antibodies to erythropoietin-stimulating drugs is an important problem of therapy with recombinant human erythropoietin (EPO). It leads to changes in the pharmacokinetic profile and decreased therapeutic efficiency. Upon long-term treatment with EPO preparations, neutralizing antibodie...
Main Authors: | A. M. Kudryashova, N. A. Mikhailova, O. V. Borisova |
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Format: | Article |
Language: | Russian |
Published: |
SPb RAACI
2018-12-01
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Series: | Medicinskaâ Immunologiâ |
Subjects: | |
Online Access: | https://www.mimmun.ru/mimmun/article/view/1682 |
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