RON kinase isoforms demonstrate variable cell motility in normal cells
Introduction: Aberrant RON (Recepteur d'Origine Nantais) tyrosine kinase activation causes the epithelial cell to evade normal growth pathways, resulting in unregulated cell proliferation, increased cell motility and decreased apoptosis. Wildtype (wt) RON has been shown to play a role in metast...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844016310064 |