RON kinase isoforms demonstrate variable cell motility in normal cells

Introduction: Aberrant RON (Recepteur d'Origine Nantais) tyrosine kinase activation causes the epithelial cell to evade normal growth pathways, resulting in unregulated cell proliferation, increased cell motility and decreased apoptosis. Wildtype (wt) RON has been shown to play a role in metast...

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Bibliographic Details
Main Authors: Alissa Greenbaum, Ashwani Rajput, Guanghua Wan
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016310064