Detection of FLT3-ITDMutation in Twenty ChildwithAcuteMyeloidLeukemia in One Iraqi Teaching Hospital

Detection of FLT3-ITDMutation in Twenty ChildwithAcuteMyeloidLeukemia in One Iraqi Teaching Hospital

Background:Pediatric acute myeloid leukemia (AML) has a poor prognosis, and novel therapies are needed. The FLT3 tyrosine kinase inhibitorsrepresents a promising target in pediatric AML. Objectives:This study was done to estimate the frequency of FLT3- ITD mutation in childhood acute myeloid leukem...

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Bibliographic Details
Main Authors: Ethar k. Dhahir, Subh S. Al-Mudallel, Maysaa A. Dhahi
Format: Article
Language:English
Published: Faculty of Medicine University of Baghdad 2012-07-01
Series:مجلة كلية الطب
Subjects:
Childhood leukemia,acute myeloid leukemia,FMS-related tyrosine kinase gene, internal tandem duplicationmutation,polymerase chain reaction,prognosis.
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/743

Internet

http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/743

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