Low dose endotoxin priming is accountable for coagulation abnormalities and organ damage observed in the Shwartzman reaction. A comparison between a single-dose endotoxemia model and a double-hit endotoxin-induced Shwartzman reaction
<p>Abstract</p> <p>The clinical response of sepsis to a systemic inflammatory infection may be complicated by disseminated intravascular coagulation or DIC. In order to experimentally study the syndrome of DIC, we aimed for a severe sepsis model complicated by disseminated coagulat...
Main Authors: | Cate Hugo, Slofstra Sjoukje H, Spek C Arnold |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-08-01
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Series: | Thrombosis Journal |
Online Access: | http://www.thrombosisjournal.com/content/4/1/13 |
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