Interleukin-1β Protects Neurons against Oxidant-Induced Injury via the Promotion of Astrocyte Glutathione Production

Interleukin-1β Protects Neurons against Oxidant-Induced Injury via the Promotion of Astrocyte Glutathione Production

Interleukin-1β (IL-1β), a key cytokine that drives neuroinflammation in the Central Nervous System (CNS), is enhanced in many neurological diseases/disorders. Although IL-1β contributes to and/or sustains pathophysiological processes in the CNS, we recently demonstrated th...

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Bibliographic Details
Main Authors: Twinkle Chowdhury, Matthew F. Allen, Trista L. Thorn, Yan He, Sandra J. Hewett
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Antioxidants
Subjects:
Interleukin 1β
neuroinflammation
neuroprotection
glutathione
astrocyte
neuronal injury
antioxidant
non-cell-autonomous protection
Online Access:http://www.mdpi.com/2076-3921/7/8/100

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