Brown adipose tissue harbors a distinct sub-population of regulatory T cells.

Regulatory T (Treg) cells are critical determinants of both immune responses and metabolic control. Here we show that systemic ablation of Treg cells compromised the adaptation of whole-body energy expenditure to cold exposure, correlating with impairment in thermogenic marker gene expression and ma...

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Bibliographic Details
Main Authors: Dasa Medrikova, Tjeerd P Sijmonsma, Katharina Sowodniok, David M Richards, Michael Delacher, Carsten Sticht, Norbert Gretz, Tobias Schafmeier, Markus Feuerer, Stephan Herzig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4340926?pdf=render