Modulation of ERQC and ERAD: A Broad-Spectrum Spanner in the Works of Cancer Cells?

Modulation of ERQC and ERAD: A Broad-Spectrum Spanner in the Works of Cancer Cells?

Endoplasmic reticulum glycoprotein folding quality control (ERQC) and ER-associated degradation (ERAD) preside over cellular glycoprotein secretion and maintain steady glycoproteostasis. When cells turn malignant, cancer cell plasticity is affected and supported either by point mutations, preferenti...

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Bibliographic Details
Main Authors: Gábor Tax, Andrea Lia, Angelo Santino, Pietro Roversi
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2019/8384913

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