Optimization of the spherical integrity for sustained-release alginate microcarriers-encapsulated doxorubicin by the Taguchi method

Optimization of the spherical integrity for sustained-release alginate microcarriers-encapsulated doxorubicin by the Taguchi method

Abstract This study aimed to develop biodegradable calcium alginate microcarriers with uniform particle size and spherical integrity for sustained-release targeting transarterial chemoembolization. To determine related parameters including the ratio of cross-linking volume (sodium alginate: CaCl2),...

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Bibliographic Details
Main Authors:	C. T. Pan, S. T. Chien, T. C. Chiang, C. K. Yen, S. Y. Wang, Z. H. Wen, C. Y. Yu, Y. L. Shiue
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-12-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-020-78813-1

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