Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production.

Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production.

Fibrosis is a significant health problem associated with a chronic inflammatory reaction. The precise mechanisms involved in the fibrotic process are still poorly understood. However, given that inflammation is a major causative factor, immunomodulation is a possible therapeutic approach to reduce f...

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Bibliographic Details
Main Authors: Guadalupe T González-Mateo, Vanessa Fernández-Míllara, Teresa Bellón, Georgios Liappas, Marta Ruiz-Ortega, Manuel López-Cabrera, Rafael Selgas, Luiz S Aroeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4184804?pdf=render

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http://europepmc.org/articles/PMC4184804?pdf=render

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