BRCA1/2 associated cancer susceptibility: a clinical overview
The most frequently identified genetic cause of breast cancer is the germline mutation of BRCA1 and 2 genes. The carriers of these mutations are at high risk for breast and ovarian cancers and increased risk for pancreatic and prostate cancers. Personal and family history are routinely used to ident...
Main Author: | Lypas Georgios |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2016-06-01
|
Series: | Forum of Clinical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1515/fco-2015-0022 |
Similar Items
-
A Clinical Trial to Increase the Identification, Genetic Counseling Referral and Genetic Testing of Women at risk for Hereditary Breast and/or Ovarian Cancer
by: Ceceilia Bellcross, et al.
Published: (2017-07-01) -
Hereditary breast cancer: genetic and clinical hetergeneity, genetic testing, prophylactic surgery
by: L. N. Lyubchenko, et al.
Published: (2015-06-01) -
THE IMPACT OF GENETIC COUNSELING ON CLINICAL DECISION MAKING AMONG WOMEN EVALUATED FOR HEREDITARY BREAST AND OVARIAN CANCER RISK
by: PRITZLAFF, MARY ELIZABETH
Published: (2001) -
BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
by: V. N. Dmitriev, et al.
Published: (2014-07-01) -
DNA-testing for <it>BRCA1/2</it> prior to genetic counselling in patients with breast cancer: design of an intervention study, DNA-direct
by: Sie Aisha S, et al.
Published: (2012-05-01)