Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides
ADP-ribosylated peptides are important molecular tools, however, the lack of effective synthetic methods hinders the access to their complex structures. Here, the authors present a biomimetic α-selective ribosylation reaction coupled with click chemistry ultimately providing a two-step modular synth...
Main Authors: | Anlian Zhu, Xin Li, Lili Bai, Gongming Zhu, Yuanyang Guo, Jianwei Lin, Yiwen Cui, Gaofei Tian, Lihe Zhang, Jianji Wang, Xiang David Li, Lingjun Li |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-19409-1 |
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