Screening for potential targets to reduce stenosis in bioprosthetic heart valves

Abstract Progressive stenosis is one of the main factors that limit the lifetime of bioprosthetic valved conduits. To improve long-term performance we aimed to identify targets that inhibit pannus formation on conduit walls. From 11 explanted, obstructed, RNAlater presevered pulmonary valved conduit...

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Bibliographic Details
Main Authors: Rudi Foth, Orr Shomroni, Matthias Sigler, Jürgen Hörer, Julie Cleuziou, Thomas Paul, Katja Eildermann
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81340-2