Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no effective treatment. The epithelial-mesenchymal transition (EMT) is a critical stage during the development of fibrosis. To assess the effect of sulforaphane (SFN) on the EMT and fibrosis using an in v...

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Bibliographic Details
Main Authors: Sun Young Kyung, Dae Young Kim, Jin Young Yoon, Eun Suk Son, Yu Jin Kim, Jeong Woong Park, Sung Hwan Jeong
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Idiopathic pulmonary fibrosis
Bleomycin
Sulforaphane
Epithelial-mesenchymal transition
Online Access:http://link.springer.com/article/10.1186/s40360-018-0204-7

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