Recent Advances on Endocrine Disrupting Effects of UV Filters

• Main Authors: Jiaying Wang, Liumeng Pan, Shenggan Wu, Liping Lu, Yiwen Xu, Yanye Zhu, Ming Guo, Shulin Zhuang
• Format: Article
• Language: English
• Published: MDPI AG 2016-08-01
• Series: International Journal of Environmental Research and Public Health
• Subjects: ultraviolet filters; cosmetics; endocrine disrupting effects; nuclear receptor
• Online Access: http://www.mdpi.com/1660-4601/13/8/782

Ultraviolet (UV) filters are used widely in cosmetics, plastics, adhesives and other industrial products to protect human skin or products against direct exposure to deleterious UV radiation. With growing usage and mis-disposition of UV filters, they currently represent a new class of contaminants of emerging concern with increasingly reported adverse effects to humans and other organisms. Exposure to UV filters induce various endocrine disrupting effects, as revealed by increasing number of toxicological studies performed in recent years. It is necessary to compile a systematic review on the current research status on endocrine disrupting effects of UV filters toward different organisms. We therefore summarized the recent advances on the evaluation of the potential endocrine disruptors and the mechanism of toxicity for many kinds of UV filters such as benzophenones, camphor derivatives and cinnamate derivatives.