Using molecular markers to characterize productivity in Chinese hamster ovary cell lines.

Selection of high producing cell lines to produce maximum product concentration is a challenging and time consuming task for the biopharmaceutical industry. The identification of early markers to predict high productivity will significantly reduce the time required for new cell line development. Thi...

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Bibliographic Details
Main Authors: Raihana Z Edros, Susan McDonnell, Mohamed Al-Rubeai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3798306?pdf=render