Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions

Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions

Drugs targeting immune checkpoint molecules have been found effective in melanoma, lung cancer, and other malignancies treatment. Recent studies on breast cancer demonstrated the significance of inhibitory anti-CTLA-4 and anti-PD-1 in the regulation of disease progression. However, seemingly the sam...

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Bibliographic Details
Main Authors: Kamil Grubczak, Anna Kretowska-Grunwald, Dawid Groth, Izabela Poplawska, Andrzej Eljaszewicz, Lukasz Bolkun, Aleksandra Starosz, Jordan M. Holl, Marta Mysliwiec, Joanna Kruszewska, Marek Z. Wojtukiewicz, Marcin Moniuszko
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
immune checkpoint inhibitors
CTLA-4
PD-1
breast cancer
anti-tumor immunity
Online Access:https://www.mdpi.com/2073-4409/10/8/2044

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