No evidence for mutations in exons 1, 8 and 18 of the patched gene in sporadic skin lesions of Brazilian patients

No evidence for mutations in exons 1, 8 and 18 of the patched gene in sporadic skin lesions of Brazilian patients

There is strong evidence that the patched (PTCH) gene is a gene for susceptibility to the nevoid basal cell carcinoma syndrome. PTCH has also been shown to mutate in both familial and sporadic basal cell carcinomas. However, mutations of the gene seem to be rare in squamous cell carcinomas. In order...

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Bibliographic Details
Main Authors: Granja F., Santarosa P.L., Leite J.L.A.A.P., Ward L.S.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2003-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Skin
Cancer
PTCH
Mutation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000400006

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