BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility

BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility

<p>Abstract</p> <p>Background</p> <p>The reciprocal (9;22) translocation fuses the <it>bcr </it>(breakpoint cluster region) gene on chromosome 22 to the <it>abl </it>(Abelson-leukemia-virus) gene on chromosome 9. Depending on the breakpoint on ch...

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Bibliographic Details
Main Authors: Puccetti Elena, Beissert Tim, Güller Saskia, Zheng Xiaomin, Ruthardt Martin
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/262

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