Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children

Introduction: There is a need to more clearly understand the characteristics of breathing patterns in children with cleft palate inthe first year of life, as there is little data available to guide current practice. Pierre Robin patients are known to have a higher incidence, however we hypothesised...

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Main Authors: Justice E. Reilly, Craig J. H., Neil A. Gibson, Tony Moores, Arup K. Ray, Mark F. Devlin, David M. Wynne
Format: Article
Language:English
Published: Dentitio 2014-09-01
Series:South European Journal of Orthodontics and Dentofacial Research
Online Access:http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=189375
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spelling doaj-1f14f8c329334c93b5b7ad66570081c02020-11-24T23:42:34ZengDentitioSouth European Journal of Orthodontics and Dentofacial Research1849-52491849-38582014-09-011110.5937/sejodr1-15236 Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft childrenJustice E. ReillyCraig J. H. Neil A. GibsonTony MooresArup K. RayMark F. DevlinDavid M. WynneIntroduction: There is a need to more clearly understand the characteristics of breathing patterns in children with cleft palate inthe first year of life, as there is little data available to guide current practice. Pierre Robin patients are known to have a higher incidence, however we hypothesised sleep breathing disturbance is not confined to this sub-group of cleft patient. Methods: We conducted a prospective observational study of sleep disordered breathing patterns in a cohort of infants with oronasal clefts (cleft palate with or without cleft lip) to describe the spectrum of sleep breathing patterns both pre and post palate repair. Sleep breathing studies were performed pre- and post-operatively in sequential infants referred to a regional cleft lip andpalate unit. Results of sleep breathing studies were analysed according to American Academy of Sleep Medicine scoring guidelines and correlated with clinical history and details of peri-operative respiratory compromise. The degree of sleep disordered breathingwas characterised using desaturation indices (number of desaturations from baseline SpO2 of >=4%, per hour). Results: Thirty-nine infants were included in this study, twenty-five female and fourteen male. Twelve had isolated Cleft Palate aspart of an associated syndrome. Patients were categorised into Isolated Cleft Palate, Isolated Cleft Palate in the context of Pierre Robin Sequence, and those with Cleft Lip and Palate. All groups demonstrated some degree of sleep breathing abnormality. Not unsurprisingly the eight infants with Pierre Robin Sequence had a significantly higher desaturation index before surgicalintervention (p=0.043), and were more likely to require a pre-operative airway intervention (p=0.009). Palate repair in this group did not alter the relative distribution of patients in each severity category of sleep disorder breathing. Surgical repair ofthe secondary palate in the remaining children was associated with some improvement but by no means complete resolution of their sleep disordered breathing patterns. Conclusions: We conclude that sleep breathing disturbance is not confined to Pierre Robin patients alone and all cleft palate patients should undergo pre-operative and post-operative sleep breathing analysis.http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=189375
collection DOAJ
language English
format Article
sources DOAJ
author Justice E. Reilly
Craig J. H.
Neil A. Gibson
Tony Moores
Arup K. Ray
Mark F. Devlin
David M. Wynne
spellingShingle Justice E. Reilly
Craig J. H.
Neil A. Gibson
Tony Moores
Arup K. Ray
Mark F. Devlin
David M. Wynne
Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
South European Journal of Orthodontics and Dentofacial Research
author_facet Justice E. Reilly
Craig J. H.
Neil A. Gibson
Tony Moores
Arup K. Ray
Mark F. Devlin
David M. Wynne
author_sort Justice E. Reilly
title Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
title_short Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
title_full Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
title_fullStr Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
title_full_unstemmed Evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
title_sort evaluation of changes in sleep breathing patterns after primary palatoplasty in cleft children
publisher Dentitio
series South European Journal of Orthodontics and Dentofacial Research
issn 1849-5249
1849-3858
publishDate 2014-09-01
description Introduction: There is a need to more clearly understand the characteristics of breathing patterns in children with cleft palate inthe first year of life, as there is little data available to guide current practice. Pierre Robin patients are known to have a higher incidence, however we hypothesised sleep breathing disturbance is not confined to this sub-group of cleft patient. Methods: We conducted a prospective observational study of sleep disordered breathing patterns in a cohort of infants with oronasal clefts (cleft palate with or without cleft lip) to describe the spectrum of sleep breathing patterns both pre and post palate repair. Sleep breathing studies were performed pre- and post-operatively in sequential infants referred to a regional cleft lip andpalate unit. Results of sleep breathing studies were analysed according to American Academy of Sleep Medicine scoring guidelines and correlated with clinical history and details of peri-operative respiratory compromise. The degree of sleep disordered breathingwas characterised using desaturation indices (number of desaturations from baseline SpO2 of >=4%, per hour). Results: Thirty-nine infants were included in this study, twenty-five female and fourteen male. Twelve had isolated Cleft Palate aspart of an associated syndrome. Patients were categorised into Isolated Cleft Palate, Isolated Cleft Palate in the context of Pierre Robin Sequence, and those with Cleft Lip and Palate. All groups demonstrated some degree of sleep breathing abnormality. Not unsurprisingly the eight infants with Pierre Robin Sequence had a significantly higher desaturation index before surgicalintervention (p=0.043), and were more likely to require a pre-operative airway intervention (p=0.009). Palate repair in this group did not alter the relative distribution of patients in each severity category of sleep disorder breathing. Surgical repair ofthe secondary palate in the remaining children was associated with some improvement but by no means complete resolution of their sleep disordered breathing patterns. Conclusions: We conclude that sleep breathing disturbance is not confined to Pierre Robin patients alone and all cleft palate patients should undergo pre-operative and post-operative sleep breathing analysis.
url http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=189375
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