PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality

Several methods have been developed to predict effects of amino acid substitutions on protein stability. Benchmark datasets are essential for method training and testing and have numerous requirements including that the data is representative for the investigated phenomenon. Available machine learni...

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Bibliographic Details
Main Authors: Yang Yang, Siddhaling Urolagin, Abhishek Niroula, Xuesong Ding, Bairong Shen, Mauno Vihinen
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/4/1009