Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives

Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives

A simple method for the synthesis of the title compounds by an efficient in-situ reduction and cyclization reactions of aromatic aldehydes, tert-butyl 2,4-dioxopiperidine-1-carboxylate and 5-nitro-1H-indazole or 6-nitro-1H-indazole was developed.

Bibliographic Details
Main Authors: Chen Dong-Mei, Liu Jia-Yan, Wei Ming, Wang Bing-Wei, Chu Ruo-Han, Chen Dong-Sheng
Format: Article
Language:English
Published: De Gruyter 2019-04-01
Series:Heterocyclic Communications
Subjects:
in-situ reduction
nitro compounds
indazolo [5,4-b][1,6]naphthyridine
indazolo[6,7-b][1,6]naphthyridine
Online Access:https://doi.org/10.1515/hc-2019-0006

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