Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives

A simple method for the synthesis of the title compounds by an efficient in-situ reduction and cyclization reactions of aromatic aldehydes, tert-butyl 2,4-dioxopiperidine-1-carboxylate and 5-nitro-1H-indazole or 6-nitro-1H-indazole was developed.

Bibliographic Details
Main Authors:	Chen Dong-Mei, Liu Jia-Yan, Wei Ming, Wang Bing-Wei, Chu Ruo-Han, Chen Dong-Sheng
Format:	Article
Language:	English
Published:	De Gruyter 2019-04-01
Series:	Heterocyclic Communications
Subjects:	in-situ reduction nitro compounds indazolo [5,4-b][1,6]naphthyridine indazolo[6,7-b][1,6]naphthyridine
Online Access:	https://doi.org/10.1515/hc-2019-0006

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spelling	doaj-1efeb1fe49884762b67b4e500e6324762021-09-06T19:19:48ZengDe GruyterHeterocyclic Communications2191-01972019-04-01251152110.1515/hc-2019-0006Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivativesChen Dong-Mei0Liu Jia-Yan1Wei Ming2Wang Bing-Wei3Chu Ruo-Han4Chen Dong-Sheng5Kangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu, People’s Republic of ChinaKangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu, People’s Republic of ChinaKangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu, People’s Republic of ChinaKangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu, People’s Republic of ChinaKangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu, People’s Republic of ChinaKangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu, People’s Republic of ChinaA simple method for the synthesis of the title compounds by an efficient in-situ reduction and cyclization reactions of aromatic aldehydes, tert-butyl 2,4-dioxopiperidine-1-carboxylate and 5-nitro-1H-indazole or 6-nitro-1H-indazole was developed.https://doi.org/10.1515/hc-2019-0006in-situ reductionnitro compoundsindazolo [5,4-b][1,6]naphthyridineindazolo[6,7-b][1,6]naphthyridine
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Chen Dong-Mei Liu Jia-Yan Wei Ming Wang Bing-Wei Chu Ruo-Han Chen Dong-Sheng
spellingShingle	Chen Dong-Mei Liu Jia-Yan Wei Ming Wang Bing-Wei Chu Ruo-Han Chen Dong-Sheng Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives Heterocyclic Communications in-situ reduction nitro compounds indazolo [5,4-b][1,6]naphthyridine indazolo[6,7-b][1,6]naphthyridine
author_facet	Chen Dong-Mei Liu Jia-Yan Wei Ming Wang Bing-Wei Chu Ruo-Han Chen Dong-Sheng
author_sort	Chen Dong-Mei
title	Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives
title_short	Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives
title_full	Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives
title_fullStr	Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives
title_full_unstemmed	Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives
title_sort	synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives
publisher	De Gruyter
series	Heterocyclic Communications
issn	2191-0197
publishDate	2019-04-01
description	A simple method for the synthesis of the title compounds by an efficient in-situ reduction and cyclization reactions of aromatic aldehydes, tert-butyl 2,4-dioxopiperidine-1-carboxylate and 5-nitro-1H-indazole or 6-nitro-1H-indazole was developed.
topic	in-situ reduction nitro compounds indazolo [5,4-b][1,6]naphthyridine indazolo[6,7-b][1,6]naphthyridine
url	https://doi.org/10.1515/hc-2019-0006
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Synthesis of indazolo[5,4-b][1,6]naphthyridine and indazolo[6,7-b][1,6]naphthyridine derivatives

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