Well-being, familial risk, and transfusion interval in thalassemia-affected families: A two-step cluster analysis

BACKGROUND: Thalassemia is an inherited blood disorder which is one of the common genetic disorders among children that is increasing worldwide. AIM AND OBJECTIVE: This study aimed to identify clustering patterns among thalassemia-affected families based on their well-being, transfusion interval, an...

Full description

Bibliographic Details
Main Authors: Arulmani Thiyagarajan, M Bhagvandas, Kalpana Kosalram, Sudip Bhattacharya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Education and Health Promotion
Subjects:
Online Access:http://www.jehp.net/article.asp?issn=2277-9531;year=2019;volume=8;issue=1;spage=89;epage=89;aulast=Thiyagarajan
Description
Summary:BACKGROUND: Thalassemia is an inherited blood disorder which is one of the common genetic disorders among children that is increasing worldwide. AIM AND OBJECTIVE: This study aimed to identify clustering patterns among thalassemia-affected families based on their well-being, transfusion interval, and risk factors using two-step cluster analysis (TCA). METHODS: The study design is a descriptive, analytical cross-sectional study. The study sample consisted of 125 thalassemia children along with either one of the parents who referred to a thalassemia treatment center of a pediatric hospital in Chennai, Tamil Nadu. The parents and children were evaluated using the Ryff Psychological Well-being Scale and Kidscreen Questionnaire respectively. Data were analyzed using SPSS version 16.0 software. RESULTS: Out of 125 parents, 86 were father (68.8%) and 39 were mother (31.2%). The mean age of parents was 38 years. Similarly, out of 125 thalassemia-affected children, the mean age of children was 13 years. Six clusters were deducted from the TCA. Parents' well-being variable does not have discriminating power to form cluster division. Three cluster formations were meaningful. CONCLUSION: TCA, in this study, helps in finding the clusters of families with thalassemia-affected children associated with poor well-being and familial risks, which require attention for medical counseling.
ISSN:2277-9531