Development and External Validation of a Novel 12-Gene Signature for Prediction of Overall Survival in Muscle-Invasive Bladder Cancer

Development and External Validation of a Novel 12-Gene Signature for Prediction of Overall Survival in Muscle-Invasive Bladder Cancer

Purpose: We aimed to develop and validate a novel gene signature from published data and improve the prediction of survival in muscle-invasive bladder cancer (MIBC).Methods: We searched the published gene signatures associated with the overall survival (OS) of MIBC and compiled all 274 genes to deve...

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Bibliographic Details
Main Authors: MierXiati Abudurexiti, Huyang Xie, Zhongwei Jia, Yiping Zhu, Yao Zhu, Guohai Shi, Hailiang Zhang, Bo Dai, Fangning Wan, Yijun Shen, Dingwei Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
muscle-invasive bladder cancer
gene signature
overall survival
prognosis
TCGA
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00856/full

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