A Convenient and Robust Test to Quantify Interocular Suppression for Children With Amblyopia

• Main Authors: Hui Chen, Zhifen He, Jinling Xu, Yu Mao, Yunjie Liang, Danli Lin, Meiping Xu, Zhiyue Dai, Xiaoxin Chen, Jiawei Zhou, Xinping Yu
• Format: Article
• Language: English
• Published: SAGE Publishing 2019-07-01
• Series: i-Perception
• Online Access: https://doi.org/10.1177/2041669519864971

Interocular suppression was quantified by the interocular luminance difference that was needed when the two eyes were balanced in discriminating a black–white stripe formed butterfly stimulus, which was dichoptically presented through polarized glasses. Stronger interocular suppression was found in amblyopes than that in controls at both the near (33 cm, 0.95 ± 1.00 vs. 0.14 ± 0.18, p  < .001) and far (5 m, 2.18 ± 0.97 vs. 0.24 ± 0.16, p  < .001) viewing distances. The interocular suppression in amblyopes was significantly correlated with the interocular visual acuity difference, the visual acuity of amblyopic eye, the Worth-4-Dot test, and the stereo acuity at both the near and far distances (for all cases, p  < .001). Our new test enables convenient and robust measurements of interocular suppression in children with amblyopia. The measured interocular suppression is in agreement with other clinical measures.