Oxytocin-Dependent Regulation of TRPs Expression in Trigeminal Ganglion Neurons Attenuates Orofacial Neuropathic Pain Following Infraorbital Nerve Injury in Rats

Oxytocin-Dependent Regulation of TRPs Expression in Trigeminal Ganglion Neurons Attenuates Orofacial Neuropathic Pain Following Infraorbital Nerve Injury in Rats

We evaluated the mechanisms underlying the oxytocin (OXT)-induced analgesic effect on orofacial neuropathic pain following infraorbital nerve injury (IONI). IONI was established through tight ligation of one-third of the infraorbital nerve thickness. Subsequently, the head withdrawal threshold for m...

Full description

Bibliographic Details
Main Authors: Masatoshi Ando, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Akihiko Furukawa, Tatsuki Oto, Takanobu Inada, Tomoyuki Matsui, Chikashi Fukaya, Noboru Noma, Masakazu Okubo, Yoshiyuki Yonehara, Tadayoshi Kaneko, Koichi Iwata, Masamichi Shinoda
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
oxytocin
TRPV1
TRPV4
infraorbital nerve injury
orofacial mechanical allodynia
Online Access:https://www.mdpi.com/1422-0067/21/23/9173

Internet

https://www.mdpi.com/1422-0067/21/23/9173

Similar Items