Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

Summary: To dissect the mechanisms underlying the inflation of variants in the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) genome, we present a large-scale analysis of intra-host genomic diversity, which reveals that most samples exhibit heterogeneous genomic architectures, due to t...

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Bibliographic Details
Main Authors: Alex Graudenzi, Davide Maspero, Fabrizio Angaroni, Rocco Piazza, Daniele Ramazzotti
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Genetics
Phylogenetics
Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000845

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